Transitional cell carcinoma of the bladder.
نویسنده
چکیده
Approximately 70% to 85% of patients with transitional cell carcinoma of the bladder present with tumors that are confined to the mucosa or submucosa. Recent articles have proposed that these tumors should be classified in one major group and treated in a similar fashion. Although a number of molecular and biologic markers can be used to segregate more aggressive tumors from those with little mortal threat, it is almost impossible to predict the outcome of patients individually. Unless such categorization is available, recommending a more radical or more liberal approach is prone to errors. Current available data suggest that selected cohorts of patients with limited lymph node involvement may benefit from pelvic lymph node dissection with radical cystectomy. To obtain sustained survival advantage, however, more efficacious chemotherapy regimens are needed because sole-dose intensification in the standard protocols will not be sufficient to achieve this goal.
منابع مشابه
Lymphoepithelial – Like Carcinoma with Papillary Transitional Cell Carcinoma of the Urinary Bladder Associated with Carcinoma in situ Changes of the Urothelium; A Case Report and Review of Literature
Lymphoepithelial - like carcinoma, is rarely recognized in the urinary bladder and less commonly occurs with papillary transitional cell carcinoma i.e. mixed pattern. Also, less uncommon is the occurrence of carcinoma in situ changes in the adjacent urothelium of these tumors. Here, a case of lymphoepithelial – like carcinoma and papillary transitional cell carcinoma associated with carci...
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Background and Aims: Immunohistochemical tests are one of the most important tests, which are under study to determine the prognosis of the cancers such as transitional cell carcinoma. By the time, flexible cystoscopy and urine cytology are the routine tests for following up the patients with transitional cell carcinoma, which are both operator dependent. On the other hand, cystoscopy is an inv...
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Objective: Transitional cell carcinoma (TCC) of the urinary bladder is the second common cancer of the genitourinary tract. Several parameters such as clinical and pathological parameters, molecular factors, and etc play a role in determination of prognosis and type of treatment. In this research study, ...
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عنوان ژورنال:
- Current opinion in oncology
دوره 6 3 شماره
صفحات -
تاریخ انتشار 1979